nrdI

nrdI
168

flavodoxin, ribonucleoside-diphosphate reductase

Locus
BSU_17370
Molecular weight
14.46 kDa
Isoelectric point
8.58
Protein length
130 aaSequenceBlast
Gene length
393 bpSequenceBlast
Function
synthesis of deoxyribonucleoside triphosphates
Product
ribonucleoside-diphosphate reductase
Essential
yes
Synonyms
nrdI, ymaA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1780 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,868,617  1,869,009
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
Provides oxidant (O2-) for assembly of dimanganic-tyrosyl radical (MnIII2-Y) cofactor in NrdF. PubMed
Protein family
nrdI family (with YosM, according to UniProt)
Cofactors
FMN PubMed
Structure
1RLJ (PDB)
P50618 (AlphaFold)
Paralogous protein(s)
YosM
Expression and Regulation
Operons
Genes
nrdI-nrdE-nrdF-ymaB
Description
PubMed
Regulation
expressed under anaerobic conditions (ResD) PubMed
Regulatory mechanism
ResD: activation, PubMed, in resD regulon
NrdR: repression, (predicted) PubMed, in nrdR regulon
PerR: transcription repression, PubMed, in perR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Additional information
A ncRNA is predicted between 'ymzA' and 'nrdI' PubMed
Open in new tab

nrdI→ymaB

2025-03-27 16:39:04

ghost

114

9d160ac30c7745496a34c93be2b3a105e0e35c39

32952B230D636C27ED0B2D37BD2B3FCE31A938B1

Genes
ymzA-nrdI-nrdE-nrdF-ymaB
Description
PubMed
Open in new tab

ymzA→ymaB

2025-03-31 00:14:28

Jstuelk

119

c327eefb1356b60d6946dc8bb1110dce66ded764

3940914A8E31A6E8EACC40EBB2BDE0A966EB921D

References
Reviews
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Original Publications
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1EA0595C74359A36B9161CFD531CA894C5E66E25

Page visits: 4688

Time of last update: 2025-03-30 11:56:10

Author of last update: Melvin.boenninger