bglS

bglS
168

endo-beta-1,3-1,4 glucanase

Locus
BSU_39070
Molecular weight
27.12 kDa
Isoelectric point
6.48
Protein length
242 aaSequenceBlast
Gene length
729 bpSequenceBlast
Function
lichenan degradation
Product
endo-beta-1,3-1,4 glucanase
Essential
no
E.C.
3.2.1.73
Synonyms
bglS, bgl, licS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2273 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,011,842  4,012,570
The protein
Catalyzed reaction/ biological activity
Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds (according to UniProt)
Protein family
glycosyl hydrolase 16 family (single member, according to UniProt)
Domains
GH16 domain (aa 29-242) (according to UniProt)
Structure
3O5S (PDB)
P04957 (AlphaFold)
Localization
extracellular (signal peptide) PubMed
Expression and Regulation
Operons
Genes
bglS
Description
PubMed
Regulation
expressed in the stationary phase (temporal activation) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
LicT: antitermination, via binding to an RNA switch, in licT regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

bglS

2025-03-09 20:03:00

ghost

85

91e1952956e4eaadf2db4ce5361740953587bd55

232A602B1DE02FD0395CA2849617588CAA2ADF97

Genes
licT-bglS
Description
PubMed
Regulation
expressed in the stationary phase (temporal activation) PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

licT→bglS

2025-03-13 18:55:24

ghost

87

c53f5f9d65bee2f49b36b261b08f54a3681748a8

E04D349CE33F16260854D95835D7F11AFB892F8F

Genes
yxiP-licT-bglS
Description
PubMed
Open in new tab

yxiP→bglS

2025-03-10 19:54:21

Jstuelk

137

c71d4e27ae884ff063a0224636e47b3376f616d1

E9284413C9C634EA6CE5E83A3A68A4BC61C0C559

Biological materials
Mutant
GP427 (licT-bglS::erm), BGW7 (cat), both available in Jörg Stülke's lab
BKE39070 (bglS::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTGGCATTCCCCTTTC,  downstream forward: _UP4_TAATGCCAAATGTGAAAGAG
BKK39070 (bglS::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTGGCATTCCCCTTTC,  downstream forward: _UP4_TAATGCCAAATGTGAAAGAG
References
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Page visits: 6213

Time of last update: 2025-03-11 09:31:16

Author of last update: Jstuelk