kamA

kamA
168

lysine 2,3-aminomutase

Locus
BSU_19690
Molecular weight
53.91 kDa
Isoelectric point
6.04
Protein length
471 aaSequenceBlast
Gene length
1413 bpSequenceBlast
Function
unknown
Product
lysine 2,3-aminomutase
Essential
no
E.C.
5.4.3.2
Synonyms
kamA, yodO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1509 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,139,454 → 2,140,869
The protein
Catalyzed reaction/ biological activity
L-lysine --> (3S)-3,6-diaminohexanoate (according to UniProt)
Protein family
Radical SAM superfamily (according to UniProt)
Cofactors
Fe-S cluster PubMed
PLP (according to UniProt)
Structure
2A5H (PDB) (from clostridium subterminale Sb4 , 60% identity)
O34676 (AlphaFold)
Expression and Regulation
Operons
Genes
yodT-yodS-yodR-yodQ-yodP-kamA-yokU-yozE
Description
PubMed
Regulation
expressed early during sporuation in the mother cell (SigE) PubMed
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
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yodT→yozE

2025-03-31 05:12:47

Jstuelk

82

44c21f8f9a51cb42563a9e5c6caad0babb60d90a

17328CC7373AFF7A88C018C39EBE54803F7E1157

Biological materials
Mutant
MGNA-B443 (yodO::erm), available at the NBRP B. subtilis, Japan
BKE19690 (ΔkamA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAACGAACTCCTCCTCGCG,  downstream forward: _UP4_ACTGAATGCGGAGGGGATTC
BKK19690 (ΔkamA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAACGAACTCCTCCTCGCG,  downstream forward: _UP4_ACTGAATGCGGAGGGGATTC
References
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21589FEBDE54C66DE2A3DCFC2D7BF3AEEC84B44C

Page visits: 2833

Time of last update: 2025-04-02 10:30:06

Author of last update: Melvin.boenninger