czcD

czcD
168

cation exporter (antiporter), export of zinc in exchange for extracellular K+ and H+

Locus
BSU_26650
Molecular weight
34.01 kDa
Isoelectric point
5.86
Protein length
311 aaSequenceBlast
Gene length
936 bpSequenceBlast
Function
cation efflux, resistence against Zn, Cu, Co, Ni
Product
cation exporter (antiporter)
Essential
no
Synonyms
czcD, yrdO
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1230 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,723,892  2,724,827
The protein
Catalyzed reaction/ biological activity
antiport of cytoplasmic Zn2+ in exchange for extracellular K+ and H+ PubMed
Protein family
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family (according to UniProt)
Structure
O07084 (AlphaFold)
Localization
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
czcD-czcO
Description
PubMed
Regulation
induced in the presence of toxic metal ions (Zn(II), Cd(II), Co(II), Ni(II) and Cu(II)) (CzrA) PubMed
Regulatory mechanism
CzrA: repression, PubMed, in czrA regulon
Open in new tab

czcD→czcO

2025-03-03 01:55:00

ghost

72

430ab856fd55b6eef5935b0d08aeb7c4ec8a07ad

CA86623CDC188C345091326FF4E65FA2529C0CB9

Biological materials
Mutant
BKE26650 (czcD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAAAAAACTCCTCCTTAC,  downstream forward: _UP4_TAAATTTTTTATCTAACTTT
BKK26650 (czcD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAAAAAACTCCTCCTTAC,  downstream forward: _UP4_TAAATTTTTTATCTAACTTT
References
Loading

7FB5BCC16D688465A820F436F657C49625257884

Page visits: 3295

Time of last update: 2025-04-02 07:06:52

Author of last update: Jstuelk