gltX

gltX
168

glutamyl-tRNA synthetase, universally conserved protein

Locus
BSU_00920
Molecular weight
55.56 kDa
Isoelectric point
5.02
Protein length
483 aaSequenceBlast
Gene length
1452 bpSequenceBlast
Function
translation
Product
glutamyl-tRNA synthetase
Essential
yes
E.C.
6.1.1.17
Synonyms
gltX
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0008 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
111,047 112,498
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
ATP + L-glutamate + tRNAGlu --> AMP + diphosphate + L-glutamyl-tRNAGlu(according to UniProt)
Protein family
Class-I aminoacyl-tRNA synthetase family (according to UniProt)
Structure
2O5R (PDB) (from Thermotoga maritima, 41.5% identity)
P22250 (AlphaFold)
Localization
cytoplasm (according to UniProt)
Additional information
Universally conserved protein
belongs to the 100 most abundant proteins PubMed
Expression and Regulation
Operons
Genes
gltX-cysE-cysS-mrnC-yacO-rae1
Description
PubMed
Regulation
expression transiently increases in the forespore PubMed
the T-box RNA is degraded by RNase Y PubMed
Regulatory mechanism
T-box: RNA switch, overlaps a transcription terminator upstream of cysE, in T-box
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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gltX→rae1

2025-04-04 01:30:11

Jstuelk

96

9ab774439b3983729fe5811aeaf44f4bc16c609f

BCC6FA512C81F405B92E34AE44A52F949D245F3D

References
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132E91DB8C81CD8C4F5160B2C068B74DA10AE224

Page visits: 4626

Time of last update: 2025-04-05 11:22:35

Author of last update: Jstuelk