alsT

alsT
168

putative glutamine transporter

Locus
BSU_18120
Molecular weight
50.14 kDa
Isoelectric point
9.39
Protein length
465 aaSequenceBlast
Gene length
1398 bpSequenceBlast
Function
uptake of glutamine
Product
putative glutamine transporter
Essential
no
Synonyms
alsT
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1115 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,938,925 → 1,940,322
The protein
Protein family
Alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family (according to UniProt)
Structure
6CSE (PDB) (sodium/alanine symporter from Methanococcus maripaludis S2, 36% identity) PubMed
Q45068 (AlphaFold)
Paralogous protein(s)
GlnT, YrbD, YflA
Localization
cell membrane (according to Swiss-Prot),  membrane PubMed
Expression and Regulation
Operons
Genes
alsT
Description
PubMed
Regulation
repressed in the absence of good nitrogen sources (glutamine or ammonium) (tnrA) PubMed
repressed in the presence of glutamine (GlnR) PubMed
Regulatory mechanism
TnrA: repression, PubMed, in tnrA regulon
GlnR: repression, PubMed, in glnR regulon
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alsT

2025-03-15 23:16:45

Jstuelk

66

7a0c0dadf78c53fdf5241cd6ba6448013c53ae2f

4ABCFB97E4BF5587EDCA2F8D8DB489A57AAD7344

Biological materials
Mutant
GP1888 (ΔalsT::tet), available in Jörg Stülke's lab PubMed
BKE18120 (ΔalsT::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTTACCTCCCGTTTTC,  downstream forward: _UP4_TAATATAAATATAAAACAAA
BKK18120 (ΔalsT::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTTACCTCCCGTTTTC,  downstream forward: _UP4_TAATATAAATATAAAACAAA
References
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Time of last update: 2025-03-31 00:25:02

Author of last update: Jstuelk