RsbS

2010-05-12T05:33:42Z

Kumasaka: Undo revision 121994 by Kumasaka (Talk)

* '''Description:''' anti-[[RsbT]], part of the stressosome 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rsbS''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ycxS ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || anti-RsbT
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 13 kDa, 4.14
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 363 bp, 121 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rsbR]]'', ''[[rsbT]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12275]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:rsbS_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|}

__TOC__

 

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU04680

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rsbRSTUVW-sigB-rsbX.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11091]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:''' phosphorylation on Ser-59 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed]

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''Interactions:''' [[RsbS]]-[[RsbT]] {{PubMed|16321960}}, [[RsbS]]-[[RsbU]], [[RsbR]]-[[RsbS]]

* '''Localization:'''

=== Database entries ===

* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3VY9 3VY9] (complete stressosome)

* '''UniProt:''' [http://www.uniprot.org/uniprot/P42410 P42410]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU04680]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''[[rsbR]]-[[rsbS]]-[[rsbT]]-[[rsbU]]-[[rsbV]]-[[rsbW]]-[[sigB]]-[[rsbX]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed]

* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed]

* '''Regulation:''' constitutively expressed {{PubMed|20019076}}

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

* [[Bill Haldenwang]], San Antonio, USA
* [[Chet Price]], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
* [[Rick Lewis]], Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/r.lewis homepage]

=Your additional remarks=

=References=
==Reviews==
<pubmed>19704888 16319496 </pubmed>
==Original Articles==
<pubmed>8002610,8682769,9786195,8682789,10781545, 15583165,8824586,10329124,17158665, 16321960,10671474,8808936,15312768,11244072,15342582,,16321960, 8955331, 12950928, 15466036, 9179850, 18832644 ,17218307 20019076</pubmed>

[[Category:Protein-coding genes]]

RsbS

2010-05-12T05:15:26Z

Kumasaka:

* '''Description:''' anti-[[RsbT]], part of the stressosome 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''rsbS''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ycxS ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || anti-RsbT
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigB]] activity
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 13 kDa, 4.14
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 363 bp, 121 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rsbR]]'', ''[[rsbT]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12275]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:rsbS_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|}

__TOC__

 

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU04680

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/rsbRSTUVW-sigB-rsbX.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11091]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:''' phosphorylation on Ser-59 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed]

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''Interactions:''' [[RsbS]]-[[RsbT]] {{PubMed|16321960}}, [[RsbS]]-[[RsbU]], [[RsbR]]-[[RsbS]]

* '''Localization:'''

=== Database entries ===

* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=2VY9 2VY9] (complete stressosome)

* '''UniProt:''' [http://www.uniprot.org/uniprot/P42410 P42410]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU04680]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''[[rsbR]]-[[rsbS]]-[[rsbT]]-[[rsbU]]-[[rsbV]]-[[rsbW]]-[[sigB]]-[[rsbX]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed]

* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/8002610 PubMed]

* '''Regulation:''' constitutively expressed {{PubMed|20019076}}

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

* [[Bill Haldenwang]], San Antonio, USA
* [[Chet Price]], Davis, USA [http://foodscience.ucdavis.edu/price_lab/pricelab.html homepage]
* [[Rick Lewis]], Newcastle, UK [http://www.ncl.ac.uk/camb/staff/profile/r.lewis homepage]

=Your additional remarks=

=References=
==Reviews==
<pubmed>19704888 16319496 </pubmed>
==Original Articles==
<pubmed>8002610,8682769,9786195,8682789,10781545, 15583165,8824586,10329124,17158665, 16321960,10671474,8808936,15312768,11244072,15342582,,16321960, 8955331, 12950928, 15466036, 9179850, 18832644 ,17218307 20019076</pubmed>

[[Category:Protein-coding genes]]

SubtiWiki - User contributions [en]

RsbS

RsbS