SubtiWiki - User contributions [en]

YodF

2014-09-18T13:11:10Z

Dreuss1: /* Biological materials */

* '''Description:''' similar to amino acid permease 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yodF''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19580 yodF]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=YodF YodF]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 9.682
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1488 bp, 496 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yoyD]]'', ''[[ctpA]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19580 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19580 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19580 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:yodF_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yodF_2130377_2131867_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yodF_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19580]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[putative amino acid transporter]]}},
{{SubtiWiki category|[[membrane proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[TnrA regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU19580

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19580&redirect=T BSU19580]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13535]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''
** in some database, the protein is annotated as being similar to proline permease, however, it is not involved in proline transport {{PubMed|24142252}}

* '''Protein family:''' solute:sodium symporter family (SSS family)

* '''Paralogous protein(s):''' [[YhjB]]

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''[[Domains]]:'''

* '''Modification:'''

* '''[[Cofactors]]:'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''
** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19580&redirect=T BSU19580]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34745 O34745]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU19580]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yodF_2130377_2131867_1 yodF] {{PubMed|22383849}}

* '''[[Sigma factor]]:'''

* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]
** repressed in the absence of good nitrogen sources (glutamine or ammonium) ([[TnrA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]

* '''Regulatory mechanism:'''
** [[TnrA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]

* '''Additional information:'''
** number of protein molecules per cell (minimal medium with glucose and ammonium): 445 {{PubMed|24696501}}
** number of protein molecules per cell (complex medium with amino acids, without glucose): 807 {{PubMed|24696501}}

=Biological materials =

* '''Mutant:'''
** available in [[Erhard Bremer]]'s lab {{PubMed|24142252}}
** GP1887 (kan) available in [[Jörg Stülke]]'s lab
** GP1889 (''ytnA'' replaced by a spec cassette and ''yodF'' replaced by a kan cassette) available in [[Jörg Stülke]]'s lab

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>12823818,,12823818,12107147 18763711, 24142252</pubmed>

[[Category:Protein-coding genes]]

YtnA

2014-09-18T13:10:43Z

Dreuss1: /* Biological materials */

* '''Description:''' similar to proline permease 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ytnA''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30530 ytnA]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=ytnA ytnA]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 9.912
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1389 bp, 463 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytoA]]'', ''[[asnB]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30530 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30530 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30530 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:ytnA_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytnA_3124250_3125641_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:ytnA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30530]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
{{SubtiWiki category|[[utilization of amino acids]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU30530

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30530&redirect=T BSU30530]

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/asnB-ytnA.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13891]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''
** secondary amino acid transporter
** [[APC superfamily of transport proteins|amino acid, polyamine, organocation (APC) superfamily of transporters]], [http://www.tcdb.org/search/result.php?tc=2.A.3 TC 2.A.3]

* '''Paralogous protein(s):''' [[AapA]], [[GabP]], [[HutM]], [[RocC]], [[RocE]], [[YbgF]], [[YbxG]], [[YdgF]], [[YvbW]]

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''Interactions:'''

* '''Localization:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30530&redirect=T BSU30530]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34618 O34618]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU30530]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=
* '''Operon:''' ''[[asnB]]-[[ytnA]]'' {{PubMed|10498721}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytnA_3124250_3125641_-1 ytnA] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''
** GP1885 (spec) available in [[Jörg Stülke]]'s lab
** GP1889 (''ytnA'' replaced by a spec cassette and ''yodF'' replaced by a kan cassette) available in [[Jörg Stülke]]'s lab

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>10498721 </pubmed>

[[Category:Protein-coding genes]]

AlsT

2014-09-18T13:06:29Z

Dreuss1: /* Biological materials */

* '''Description:''' amino acid carrier protein 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''alsT''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || amino acid carrier protein
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || amino acid uptake
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18120 alsT]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=alsT alsT]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 9.39
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1395 bp, 465 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ynfC]]'', ''[[bglC]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18120 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18120 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18120 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:alsT_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=alsT_1938925_1940322_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:alsT_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18120]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[putative amino acid transporter]]}},
{{SubtiWiki category|[[membrane proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[TnrA regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU18120

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU18120&redirect=T BSU18120]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11798]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' sodium:alanine (SAF) symporter family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:''' cell membrane (according to Swiss-Prot), membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU18120&redirect=T BSU18120]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/Q45068 Q45068]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU18120]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=alsT_1938925_1940322_1 alsT] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''
** repressed in the absence of good nitrogen sources (glutamine or ammonium) ([[TnrA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]

* '''Regulatory mechanism:'''
** [[TnrA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''
** GP1888 (tet) available in [[Jörg Stülke]]'s lab

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>12823818,,12823818,18763711, </pubmed>

[[Category:Protein-coding genes]]

YodF

2014-09-18T13:05:53Z

Dreuss1: /* Biological materials */

* '''Description:''' similar to amino acid permease 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yodF''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19580 yodF]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=YodF YodF]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 9.682
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1488 bp, 496 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yoyD]]'', ''[[ctpA]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19580 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19580 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19580 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:yodF_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yodF_2130377_2131867_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yodF_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19580]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[putative amino acid transporter]]}},
{{SubtiWiki category|[[membrane proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[TnrA regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU19580

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19580&redirect=T BSU19580]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13535]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''
** in some database, the protein is annotated as being similar to proline permease, however, it is not involved in proline transport {{PubMed|24142252}}

* '''Protein family:''' solute:sodium symporter family (SSS family)

* '''Paralogous protein(s):''' [[YhjB]]

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''[[Domains]]:'''

* '''Modification:'''

* '''[[Cofactors]]:'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''
** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19580&redirect=T BSU19580]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34745 O34745]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU19580]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yodF_2130377_2131867_1 yodF] {{PubMed|22383849}}

* '''[[Sigma factor]]:'''

* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]
** repressed in the absence of good nitrogen sources (glutamine or ammonium) ([[TnrA]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]

* '''Regulatory mechanism:'''
** [[TnrA]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12823818 PubMed]

* '''Additional information:'''
** number of protein molecules per cell (minimal medium with glucose and ammonium): 445 {{PubMed|24696501}}
** number of protein molecules per cell (complex medium with amino acids, without glucose): 807 {{PubMed|24696501}}

=Biological materials =

* '''Mutant:'''
** available in [[Erhard Bremer]]'s lab {{PubMed|24142252}}
** GP1887 (kan) available in [[Jörg Stülke]]'s lab

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>12823818,,12823818,12107147 18763711, 24142252</pubmed>

[[Category:Protein-coding genes]]

YtnA

2014-09-18T13:04:53Z

Dreuss1: /* Biological materials */

* '''Description:''' similar to proline permease 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ytnA''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30530 ytnA]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=ytnA ytnA]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 9.912
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1389 bp, 463 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytoA]]'', ''[[asnB]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30530 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30530 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30530 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:ytnA_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytnA_3124250_3125641_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:ytnA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30530]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
{{SubtiWiki category|[[utilization of amino acids]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU30530

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30530&redirect=T BSU30530]

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/asnB-ytnA.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13891]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''
** secondary amino acid transporter
** [[APC superfamily of transport proteins|amino acid, polyamine, organocation (APC) superfamily of transporters]], [http://www.tcdb.org/search/result.php?tc=2.A.3 TC 2.A.3]

* '''Paralogous protein(s):''' [[AapA]], [[GabP]], [[HutM]], [[RocC]], [[RocE]], [[YbgF]], [[YbxG]], [[YdgF]], [[YvbW]]

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''Interactions:'''

* '''Localization:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU30530&redirect=T BSU30530]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34618 O34618]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU30530]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=
* '''Operon:''' ''[[asnB]]-[[ytnA]]'' {{PubMed|10498721}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ytnA_3124250_3125641_-1 ytnA] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''
** GP1885 (spec) available in [[Jörg Stülke]]'s lab

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>10498721 </pubmed>

[[Category:Protein-coding genes]]

YbeC

2014-09-18T13:03:27Z

Dreuss1: /* Biological materials */

Iron metabolism

2014-01-17T12:02:58Z

Dreuss1: /* Acquisition of iron/other */

{{CategoryTree
|Parents=
* 2. [[Metabolism]]
** 2.6. [[Additional metabolic pathways]]
|Neighbours=
* 2.6.1. [[Biosynthesis of cell wall components]]
* 2.6.2. [[Biosynthesis of cofactors]]
* 2.6.3. [[Phosphate metabolism]]
* 2.6.4. [[Sulfur metabolism]]
* 2.6.5. [[Iron metabolism]]
* 2.6.6. [[Miscellaneous metabolic pathways]]
|Related=
* [[Acquisition of iron]]
* [[Fur regulon]]
|}}

== Genes in this functional category ==

==[[ABC transporters]] for the[[Iron metabolism|uptake of iron/ siderophores]]==
* [[YusV]]-[[FeuB]]-[[FeuC]]-[[FeuA]]: uptake of the siderophores enterobactin and bacillibactin
* [[FhuC]]-[[FhuB]]-[[FhuG]]-[[FhuD]]-[[YxeB]]: uptake of ferrichrome und ferrioxamine
* [[YclN]]-[[YclO]]-[[YclP]]-[[YclQ]]: uptake of petrobactin (a siderophore produced by ''B. anthracis'' and ''B. cereus'')
* [[YusV]]-[[YfiZ]]-[[YfhA]]-[[YfiY]]: uptake of the siderophores schizokinen and arthrobactin
* [[YfmF]]-[[YfmD]]-[[YfmE]]-[[YfmC]]-[[YhfQ]]: uptake of iron/citrate

== Elemental iron transport system ==
* [[EfeO]]-[[EfeU]], [[EfeB]]

== Acquisition of iron/other ==
* [[besA]]
* [[btr]]
* [[cypX]]
* [[dhbA]]
* [[dhbB]]
* [[dhbC]]
* [[dhbE]]
* [[dhbF]]
* [[dps]]
* [[fbpA]]
* [[fbpB]]
* [[fbpC]]
* [[fsrA]]

* [[fur]]
* [[mrgA]]
* [[ybbA]]

* [[yhfQ]]
* [[ymfD]]
* [[yvmC]]

=== Acquisition of iron/ based on similarity ===
* [[ytoA]]
* [[yvrA]]
* [[yvrB]]
* [[yvrC]]

=== Biosynthesis of iron-sulfur clusters ===
* ''[[fra]]''
* ''[[sufA]]''
* ''[[sufB]]''
* ''[[sufC]]''
* ''[[sufD]]''
* ''[[sufS]]''
* ''[[sufU]]''

==Key reviews==
<pubmed> 20467446 16211402 12732309 23192658 </pubmed>
=Back to [[categories]]=

ArsB

2014-01-09T14:24:49Z

Dreuss1:

* '''Description:''' extrusion of arsenite 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''arsB''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yqcL ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || arsenite exporter
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of arsenate and arsenite
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25790 arsB]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 38 kDa, 9.773
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1038 bp, 346 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[arsC]]'', ''[[yqcK]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25790 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25790 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25790 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:arsB_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=arsB_2655753_2656793_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:arsB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25790]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[resistance against toxic metals]]}},
{{SubtiWiki category|[[Skin element]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[ArsR regulon]]}},
{{SubtiWiki regulon|[[SigF regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU25790

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/arsR-yqcK-arsBC.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11303]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' ACR3 family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P45946 P45946]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU25790]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=
* '''Operon:''' ''[[arsR]]-[[yqcK]]-[[arsB]]-[[arsC]]'' {{PubMed|9537360}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=arsB_2655753_2656793_-1 arsB] {{PubMed|22383849}}

* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9537360}}, [[SigF]] {{PubMed|16497325}}

* '''Regulation:'''
** expressed early during sporulation in the forespore ([[SigF]]) {{PubMed|16497325}}
** expressed in the presence of toxic metal ions (As(III), Cd(II) and Ag(I)) ([[ArsR]]) {{PubMed|9537360}}

* '''Regulatory mechanism:'''
** [[ArsR]]: transcription repression {{PubMed|9537360}}

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>9537360,16497325,,9537360, </pubmed>

[[Category:Protein-coding genes]]