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kduD [2017-05-19 09:23:14]
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
function
utilization of galacturonic acid
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.15|Utilization of hexuronate]Gene
Coordinates
2,326,683 → 2,327,447
The protein
Catalyzed reaction/ biological activity
2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH (according to Swiss-Prot)Protein family
phosphopentomutase family (according to Swiss-Prot)Paralogous protein(s)
[protein|B6FF689E65906186F3576B378650D713DB84EDDA|YcdF], [protein|3161519994609DA9360ED6E073E4A4C8C6210EFB|YdaD], [protein|EAEEA4DD9641919830A81185333A2610B964D37C|YhdF]Structure
[PDB|4HP8] (from Agrobacterium tumefaciens, 54% identity)Expression and Regulation
Operons
genes
[gene|CFAEF60AD73F18C8DB5EF042210602B149D51152|kduI]-[gene|FBBDE1E058223D5E8CEB07CAA50940A329C809E4|kduD]
description
[Pubmed|17322190]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|17322190], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|891A32A19D1353BA566FF121BBCA7B986D31D129|KdgR]: repression, [Pubmed|17322190], in [regulon|891A32A19D1353BA566FF121BBCA7B986D31D129|KdgR regulon][protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|17322190], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]regulation
induced by galacturonate ([protein|search|KdgR]) [Pubmed|17322190]view in new tabReferences
