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kduD [Mon Aug 31 2015 13:55:13 GMT+0200 (CEST)]
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kduD [Mon Aug 31 2015 13:55:13 GMT+0200 (CEST)]

2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
locus
BSU22140
pI
6.50
mw
27.00 kDa
function
utilization of galacturonic acid
essential
no
ec
1.1.1.125
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.15|Utilization of hexuronate]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources]
  • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|KdgR regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH (according to Swiss-Prot)
  • Protein family

  • phosphopentomutase family (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|kduI]-[protein|search|kduD]'' [Pubmed|17322190]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|17322190]
  • Regulation

  • induced by galacturonate ([protein|search|KdgR]) [Pubmed|17322190]
  • repressed by glucose ([protein|search|CcpA]) [Pubmed|17322190]
  • Regulatory mechanism

  • [protein|search|KdgR]: transcription repression [Pubmed|17322190]
  • [protein|search|CcpA]: transcription repression [Pubmed|17322190]
  • References

  • 17322190