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gamR [Mon Aug 31 2015 13:52:09 GMT+0200 (CEST)]
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gamR [Mon Aug 31 2015 13:52:09 GMT+0200 (CEST)]

transcriptional repressor (GntR family) of the gamA-gamP operon
locus
BSU02370
pI
5.56
mw
26.00 kDa
function
regulation of glucosamine utilization
product
transcriptional regulator (GntR family)
essential
no
synonyms
ybgA

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.3|Utilization of cell wall components]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.17|Utilization of amino sugars]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.3|Utilization of amino sugars]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • syns
    ybgA

    [SW|Categories] containing this gene/protein

  • [SW|cell wall degradation/ turnover], [SW|utilization of specific carbon sources], [SW|transcription factors and their control]
  • This gene is a member of the following [SW|regulons]

  • [SW|GamR regulon]
  • The protein

    Protein family

  • [SW|GntR family] of transcription factors
  • Effectors of protein activity

  • glucosamine-6-phosphate acts as molecular inducer that prevents GamR from binding to its operator sites in the promoter regions of the ''[protein|search|gamA]-[protein|search|gamP]'' and ''[protein|search|gamR]-[protein|search|ybgB]'' operons [Pubmed|24673833]
  • Expression and Regulation

    Operon

  • ''[protein|search|gamR]-[protein|search|ybgB]'' [Pubmed|23667565]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|23667565]
  • Regulation

  • induced by glucosamine ([protein|search|GamR]) [Pubmed|24673833,23667565]
  • Regulatory mechanism

  • [protein|search|GamR]: transcription repression [Pubmed|24673833,23667565]
  • References

    Reviews

  • 26159076
  • Original publications

  • 10627040,23667565,24673833