transcriptional repressor (GntR family) of the gamA-gamP operon
function
regulation of glucosamine utilization
product
transcriptional regulator (GntR family)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.3|Utilization of cell wall components][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.17|Utilization of amino sugars][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.3|Utilization of amino sugars][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][SW|Categories] containing this gene/protein
[SW|cell wall degradation/ turnover], [SW|utilization of specific carbon sources], [SW|transcription factors and their control]This gene is a member of the following [SW|regulons]
[SW|GamR regulon]The protein
Protein family
[SW|GntR family] of transcription factorsEffectors of protein activity
glucosamine-6-phosphate acts as molecular inducer that prevents GamR from binding to its operator sites in the promoter regions of the ''[protein|search|gamA]-[protein|search|gamP]'' and ''[protein|search|gamR]-[protein|search|ybgB]'' operons [Pubmed|24673833]Expression and Regulation
Operon
''[protein|search|gamR]-[protein|search|ybgB]'' [Pubmed|23667565][SW|Sigma factor]
[protein|search|SigA] [Pubmed|23667565]Regulation
induced by glucosamine ([protein|search|GamR]) [Pubmed|24673833,23667565]Regulatory mechanism
[protein|search|GamR]: transcription repression [Pubmed|24673833,23667565]References
Reviews
Original publications
10627040,23667565,24673833