SubtiBank SubtiBank
yqaM
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yqaM

similar to phage-related protein, skin-element
locus
BSU_26260
pI
5.39
mw
35.98 kDa
protein length
286 aa Sequence Blast
gene length
861 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element]

    • Gene

    Coordinates
    2,693,597 → 2,694,457

    Phenotypes of a mutant

  • overexpression of YqaM causes cell filamentation and abnormal chromosome segregation [Pubmed|20889742]
  • overexpression of YqaM inhibits initiation DNA replication, perhaps due to the interaction with [protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|DnaC] [Pubmed|20889742]

    • The protein

    Paralogous protein(s)

  • [protein|8766A2EE18B75E50C5369AB8B72AD934F82D7545|XkdC]

    • Structure

  • [PDB|3ECC] (Aquifex aeolicus [protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|DnaC], C-terminus of [protein|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|YqaM], corresponds to aa 135 ... 277, 29% identity) [pubmed|19013274]

    • [SW|Localization]

  • Cytoplasm (Homogeneous) [Pubmed|16479537]

    • Expression and Regulation

    Operons

    genes
    [gene|16BEDCFFB1671793061ACE4AC528D3B8EB177DC8|yqaF]-[gene|02216407B5EDB98FAF611E22B2323C819B9D58BB|yqdA]-[gene|03DAF537379754763646AF3AF2AD811B107F5302|yqaG]-[gene|F6AB74740776179E77218DB831FEE03773B7353F|yqaH]-[gene|5EA0F507F949D249D5B5B860861BBEB4197E01C5|yqaI]-[gene|CFCCFD8C6420CC1DD076B091AD3D914FC8AB22D5|yqaJ]-[gene|903E11BD2CFF3EE1A831F0F50F91741893C3DAB8|yqaK]-[gene|AB4AF9BD3E16FD72370AFC82CDD1531518053E6F|yqaL]-[gene|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|yqaM]-[gene|A9AACF8F25A1A80B3AE2A94DFC3A0E09012B55E7|yqzO]-[gene|3A89444BA25E4940C4197AACBD8B66BC1C65A493|yqaN]
    description
    [Pubmed|20889742]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|20889742], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|846161AE54F170075F2B2133A8D56FE39A5AF8D9|SknR]: repression, [Pubmed|20889742], in [regulon|846161AE54F170075F2B2133A8D56FE39A5AF8D9|SknR regulon]

    • regulation

  • not expressed during normal growth ([protein|846161AE54F170075F2B2133A8D56FE39A5AF8D9|SknR]) [Pubmed|20889742]

    • additional information

  • A [protein|search|ncRNA] is predicted between [gene|CFCCFD8C6420CC1DD076B091AD3D914FC8AB22D5|yqaJ] and [gene|5EA0F507F949D249D5B5B860861BBEB4197E01C5|yqaI] [PubMed|20525796]
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    Biological materials

    Mutant

  • BKE26260 (Δ[gene|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|yqaM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE26260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCCTTACAATAAGGACAAT, downstream forward: _UP4_CAATTAAATCATAGGTTAGG
  • BKK26260 (Δ[gene|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|yqaM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK26260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCCTTACAATAAGGACAAT, downstream forward: _UP4_CAATTAAATCATAGGTTAGG

    • References

  • 20889742,16479537,12060778,19013274