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comN
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comN

mediates post-transcriptional control of [gene|788725411B2E741103603373E43441FD036E1BA0|comE] operon expression
locus
BSU_27660
pI
4.62
mw
11.45 kDa
protein length
98 aa Sequence Blast
gene length
297 bp Sequence Blast
function
regulation of competence and DNA uptake
product
post-transcriptional regulator of [gene|788725411B2E741103603373E43441FD036E1BA0|comE] expression
essential
no
synonyms
yrzD
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]

    • Gene

    Coordinates
    2,829,152 → 2,829,448

    The protein

    Catalyzed reaction/ biological activity

  • post-transcriptional control of ''[gene|788725411B2E741103603373E43441FD036E1BA0|comEA]'' expression [Pubmed|19028902]
  • promotes the accumulation of its target ''[gene|788725411B2E741103603373E43441FD036E1BA0|comEA]'' mRNA to septal and polar sites [Pubmed|22582279]
  • required for oriC placement during spore development [Pubmed|27059541]

    • [SW|Localization]

  • localizes to the division site and cell poles in a [protein|search|DivIVA ]dependent fashion [Pubmed|22582279]

    • Expression and Regulation

    Operons

    genes
    [gene|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7|comN]-[gene|F0E7B6E000A5B06C9023C76F21551E754C8C45BA|secDF]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]
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    Biological materials

    Mutant

  • BKE27660 (Δ[gene|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7|comN]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGAATTCCACGCTCCTTT, downstream forward: _UP4_TAGCAGGTTGATTCGCACAG
  • BKK27660 (Δ[gene|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7|comN]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGAATTCCACGCTCCTTT, downstream forward: _UP4_TAGCAGGTTGATTCGCACAG

    • References

  • 19028902,22582279,27059541