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iolS
similar to dehydrogenase, may be involved in myo-inositol catabolism
function
unknown, may be involved in myo-inositol catabolism
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.16|Utilization of inositol]Gene
Coordinates
4,085,608 → 4,086,540
The protein
Protein family
[SW|Aldo/keto reductase family] (according to UniProt)Paralogous protein(s)
[protein|4DF9B105ABA64AFD5106EE75FCC9EFAB52BEFC83|YhdN], [protein|B73D729097C00BE6F3C7FF1708738783EE93C6FB|YccK][protein|B0897643562CDB25547223CCB9CFD0F9E78710E2|YqkF]: Structure
[PDB|1PZ0] [Pubmed|15019785]Expression and Regulation
Operons
genes
[gene|5F4ABBC8ECAD6F6C10EC39B2B0F0BC73F11522CE|iolR]-[gene|F1AFFACD36C75702B0BB8F0B4241A9688FB6253C|iolS]
description
[Pubmed|9226270]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|9226270], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|5F4ABBC8ECAD6F6C10EC39B2B0F0BC73F11522CE|IolR]: repression, [Pubmed|9226270], in [regulon|5F4ABBC8ECAD6F6C10EC39B2B0F0BC73F11522CE|IolR regulon]regulation
induced by inositol ([protein|search|IolR]) [Pubmed|9226270]view in new tabBiological materials
Mutant
BKE39780 (Δ[gene|F1AFFACD36C75702B0BB8F0B4241A9688FB6253C|iolS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCTGCCTCCTAGAAT, downstream forward: _UP4_TAAGAAGAAAACAGCCTTCTBKK39780 (Δ[gene|F1AFFACD36C75702B0BB8F0B4241A9688FB6253C|iolS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39780 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGATCTGCCTCCTAGAAT, downstream forward: _UP4_TAAGAAGAAAACAGCCTTCTlabs
[SW|Yasutaro Fujita], University of Fukuyama, Japan[[Ken-ichi Yoshida]], Kobe University, JapanReferences
9226270,15019785,9887260,27941785