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pksS

cytochrome P450, hydroxylase of the polyketide bacillaene produced by the pks cluster

locus

BSU_17230

6.12

43.26 kDa

protein length

405 aa Sequence Blast

gene length

1218 bp Sequence Blast

function

polyketide synthesis

product

hydroxylase of the polyketide produced by the pks cluster

essential

synonyms

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds]

[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds]

Gene

Coordinates

1,858,566 → 1,859,783

The protein

Catalyzed reaction/ biological activity

hydroxylation of dihydrobacillaene [Pubmed|17482575]

Protein family

[SW|cytochrome P450] family (according to UniProt)

Paralogous protein(s)

Structure

[PDB|4YZR]

Expression and Regulation

Operons

genes

[gene|EF0F13BB682791E167EFC350BF029B08E8A1F410|pksS]

description

[Pubmed|22383849]

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Biological materials

Mutant

BKE17230 (Δ[gene|EF0F13BB682791E167EFC350BF029B08E8A1F410|pksS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE17230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCATTCTCCTCGCCT, downstream forward: _UP4_TAACATTCAAAACGCCCCCT

BKK17230 (Δ[gene|EF0F13BB682791E167EFC350BF029B08E8A1F410|pksS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK17230 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGCATTCTCCTCGCCT, downstream forward: _UP4_TAACATTCAAAACGCCCCCT

References

17482575,21821766