3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
function
mother cell metabolism, leucine utilization
product
3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.9|Utilization of branched-chain amino acids][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|utilization of amino acids], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon]The protein
Catalyzed reaction/ biological activity
(S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate [Pubmed|19935659]Protein family
HMG-CoA lyase family (according to Swiss-Prot)Structure
[PDB|1YDO]Expression and Regulation
Operon
''[protein|search|yngJ]-[protein|search|yngI]-[protein|search|yngH]-[SW|yngHB]-[protein|search|yngG]-[protein|search|yngF]-[protein|search|yngE]'' [Pubmed|12662922][SW|Sigma factor]
[protein|search|SigE] [Pubmed|15699190,12662922]Regulation
expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,12662922]References
15699190,12662922,16330546,18943917,19935659 
