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dppC [2019-06-27 14:15:35]
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dppC [2019-06-27 14:15:35]

dipeptide [protein|search|ABC transporter] (permease)
locus
BSU12940
pI
9.81
mw
35.65 kDa
protein length
320 aa Sequence Blast
gene length
963 bp Sequence Blast
function
uptake of dipeptides
product
dipeptide [SW|ABC transporter] (permease)
essential
no
synonyms
dciAC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.3|Uptake of peptides]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,362,174 → 1,363,136

    The protein

    Protein family

  • [SW|Binding-protein-dependent transport system permease family] (according to UniProt)

    • Paralogous protein(s)

  • [protein|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|AppC], [protein|DDBCE73B6AF39E5D669475479186C93F287DA9FC|OppC]

    • [SW|Localization]

  • cell membrane [Pubmed|10092453]

    • Expression and Regulation

    Operons

    genes
    [gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]
    description
    [Pubmed|1766371]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1766371], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|7783641], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]

    • regulation

  • repressed by glucose (2.9-fold) [Pubmed|12850135]
    • view in new tab

    genes
    [gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]-[gene|C4F85F85F0C99A59145961E34B19D3AD03D2BC22|ykfA]-[gene|77EFC47449D8CC17651ED61C41AC605FCEF01270|ykfB]-[gene|D40ECAE51D9E4791C6FAAA25E2E0D0591D9FAA55|ykfC]-[gene|BB94F5388A0D1FF025E5A88A7E10AE7E4C489E5F|ykfD]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|12618455], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]
    • view in new tab

    Biological materials

    Mutant

  • BKE12940 (Δ[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE12940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA
  • BKK12940 (Δ[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK12940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA

    • References

  • 12618455,10092453,1766371,7783641,1766371