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dppC [2018-05-04 13:38:33]
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dppC [2018-05-04 13:38:33]

dipeptide ABC transporter (permease)
locus
BSU12940
pI
9.81
mw
35.65 kDa
protein length
320 aa Sequence Blast
gene length
960 bp Sequence Blast
function
uptake of dipeptides
product
dipeptide ABC transporter (permease)
essential
no
synonyms
dciAC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.3|Uptake of peptides]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,362,174 → 1,363,136

    The protein

    Protein family

  • ABC transmembrane type-1 domain (according to Swiss-Prot)

    • [SW|Localization]

  • cell membrane [Pubmed|10092453]

    • Expression and Regulation

    Operons

    genes
    [gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]
    description
    [Pubmed|1766371]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1766371], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|7783641], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]

    • regulation

  • repressed by glucose (2.9-fold) [Pubmed|12850135]
    • view in new tab

    genes
    [gene|9E922F0006DF9E84A8D5B51E9FC35B669872FF90|dppA]-[gene|062AE5FB4C778178A7F6833CB8BD9D631E461E89|dppB]-[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]-[gene|7FA72D949B930A3C7FF0391CC6CCC58EEFCA839A|dppD]-[gene|853C570CFB9382449A20BE77B44B4FE44972AA59|dppE]-[gene|C4F85F85F0C99A59145961E34B19D3AD03D2BC22|ykfA]-[gene|77EFC47449D8CC17651ED61C41AC605FCEF01270|ykfB]-[gene|D40ECAE51D9E4791C6FAAA25E2E0D0591D9FAA55|ykfC]-[gene|BB94F5388A0D1FF025E5A88A7E10AE7E4C489E5F|ykfD]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [Pubmed|12618455], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]
    • view in new tab

    Biological materials

    Mutant

  • BKE12940 (Δ[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE12940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA
  • BKK12940 (Δ[gene|EDF8D2C49FA5552B24135E12524F9035E1E01473|dppC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK12940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGTACAGGGAGATTCACAC, downstream forward: _UP4_GACCCTAAGCTGAGGAGGTA

    • References

  • 12618455,10092453,1766371,7783641,1766371