transcriptional repressor (GntR family) of the lutA-lutB-lutC operon and of lutP
function
control of lactate utilization
product
transcriptional repressor, (GntR family)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources], [SW|transcription factors and their control]Gene
Coordinates on the chromosome (coding sequence)
3,509,831 -> 3,510,490
The protein
Catalyzed reaction/ biological activity
transcriptional repressor of the'' [protein|search|lutA]-[protein|search|lutB]-[protein|search|lutC]'' operon [Pubmed|19201793]Protein family
[SW|GntR family] of transcription factorsEffectors of protein activity
lactate acts as molecular inducer [Pubmed|19201793]Expression and Regulation
[SW|Sigma factor]
[protein|search|SigA] [Pubmed|25031425]Biological materials
Mutant
TEK1 lutR::Tn10::spc [Pubmed|24196425]Expression vector
pQE60-lutR (His-tag) [Pubmed|24196425]lacZ fusion
TEK7 lutR::lacZ::erm [Pubmed|24196425]Labs working on this gene/protein
[SW|Richard Losick], Harvard Univ., Cambridge, USA [http://www.mcb.harvard.edu/Losick/ homepage][SW|Ayten Katatas], Istanbul Technical University, Istanbul, Turkey [http://www.bio.itu.edu.tr/personel_data/personel_ayten_yazgan_karatas.htm x]References
24196425,19201793,25031425,18604637 
