membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein, receptor for asparagine
function
control of chemotaxis
product
methyl-accepting chemotaxis protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.4|Membrane-bound chemoreceptors][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|motility and chemotaxis], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigD regulon]Gene
Coordinates on the chromosome (coding sequence)
3,210,445 -> 3,212,433
The protein
Paralogous protein(s)
[protein|search|McpA]Kinetic information
K(D) for asparagine: 14 myM [Pubmed|19864420]Modification
methylated at residues Gln371, Glu630, and Glu637 [Pubmed|20864474]Effectors of protein activity
asparagine (binds to the part of McpB that is exposed to the exterior) [Pubmed|19864420][SW|Localization]
cell membrane [Pubmed|18763711,21515776]localized at the cell poles, but in the presence of high asparagine concentration there is a reversible re-localization to the sides of the cell (lateral clusters) [Pubmed|21098025][SW|Interactions]
[protein|search|CheA]-[protein|search|McpB] [Pubmed|19864420][protein|search|McpB]-[protein|search|CheC] [Pubmed|11722727][protein|search|McpB]-[protein|search|CheW] [Pubmed|25039821][protein|search|McpB]-[protein|search|CheD] to increase the ability of [protein|search|McpB] to activate [protein|search|CheA] [Pubmed|25039821]Expression and Regulation
Operon
''[protein|search|mcpB]'' [Pubmed|8188684][SW|Sigma factor]
[protein|search|SigD] [Pubmed|8188684]Additional information
in minimal medium, McpB is present with 6,200 /- 1,900 molecules per cell [PubMed|21515776] References
11722727,10825179,8251536,12909020,10196193,15544802,6137212,9194713,2505839,8188684,2105313,12123464,14731274,20864474,18763711,19864420,21098025,21515776,25039821 
