SubtiBank SubtiBank
appA/1 [Mon Aug 31 2015 13:53:37 GMT+0200 (CEST)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

appA/1 [Mon Aug 31 2015 13:53:37 GMT+0200 (CEST)]

oligopeptide ABC transporter, inactive pseudogene in strain 168
locus
BSU11381
function
unknown
product
oligopeptide ABC transporter
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.3|Uptake of peptides]
  • [category|SW 6|Groups of genes] → [category|SW 6.10|Pseudogenes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|membrane proteins], [SW|pseudogenes]
  • This gene is a member of the following [SW|regulons]

  • [SW|CodY regulon], [SW|ScoC regulon], [SW|TnrA regulon]
  • The protein

    [SW|Localization]

  • attached to the cell membrane (via [protein|search|AppB]-[protein|search|AppC]) [Pubmed|10092453]
  • [SW|Interactions]

  • ([protein|search|AppD]-[protein|search|AppF])-([protein|search|AppB]-[protein|search|AppC])-[protein|search|AppA] [Pubmed|10092453]
  • Expression and Regulation

    Operon

  • ''[protein|search|appD]-[protein|search|appF]-[protein|search|appA]-[protein|search|appB]-[protein|search|appC]'' [Pubmed|7997159]
  • Regulation

  • repressed during exponential growth ([protein|search|ScoC]) [Pubmed|10383984]
  • repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|12618455]
  • Regulatory mechanism

  • [protein|search|ScoC]: transcription repression [Pubmed|10383984]
  • [protein|search|CodY]: transcription repression [Pubmed|12618455]
  • [protein|search|TnrA]: transcription activation [Pubmed|25755103]
  • Biological materials

    Mutant

  • GP2100 (D(''[protein|search|appD]-[protein|search|appF]-[protein|search|appA]-[protein|search|appB]-[protein|search|appC]'')::''spc''), available in [SW|Jörg Stülke]'s lab
  • References

  • 12618455,7997159,10092453,10383984,12618455,25755103