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adaB [Mon Aug 31 2015 13:52:04 GMT+0200 (CEST)]
O6-methylguanine-DNA methyltransferase
function
adaptive response to alkylative DNA damage
product
O6-methylguanine-DNA methyltransferase
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.4|Prophage 1][SW|Categories] containing this gene/protein
[SW|DNA repair/ recombination], [SW|prophage 1]This gene is a member of the following [SW|regulons]
[SW|AdaA regulon]The protein
Catalyzed reaction/ biological activity
DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine (according to Swiss-Prot)Protein family
MGMT family (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|adaA]-[protein|search|adaB]'' [Pubmed|2120677][SW|Sigma factor]
[protein|search|SigA] [Pubmed|2120677]Regulation
positive control by [protein|search|AdaA] [Pubmed|2120677]References
Reviews
Original publications