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adaB [Mon Aug 31 2015 13:52:04 GMT+0200 (CEST)]
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adaB [Mon Aug 31 2015 13:52:04 GMT+0200 (CEST)]

O6-methylguanine-DNA methyltransferase
locus
BSU01820
pI
6.15
mw
19.00 kDa
function
adaptive response to alkylative DNA damage
product
O6-methylguanine-DNA methyltransferase
essential
no
ec
2.1.1.63
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.4|Prophage 1]
  • [SW|Categories] containing this gene/protein

  • [SW|DNA repair/ recombination], [SW|prophage 1]
  • This gene is a member of the following [SW|regulons]

  • [SW|AdaA regulon]
  • The protein

    Catalyzed reaction/ biological activity

  • DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine (according to Swiss-Prot)
  • Protein family

  • MGMT family (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|adaA]-[protein|search|adaB]'' [Pubmed|2120677]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|2120677]
  • Regulation

  • positive control by [protein|search|AdaA] [Pubmed|2120677]
  • References

    Reviews

  • 22933559,24810496
  • Original publications

  • 2120677