N-acetyl-diaminopimelate deacetylase
function
biosynthesis of lysine and peptidoglycan
product
N-acetyl-diaminopimelate deacetylase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.6|Biosynthesis/ acquisition of lysine/ threonine][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|biosynthesis/ acquisition of amino acids], [SW|essential genes]Gene
Coordinates on the chromosome (coding sequence)
1,489,753 -> 1,490,877
Phenotypes of a mutant
essential [Pubmed|24261876,12682299]depletion of DapI results in swelling and rounding up of cells prior to lysis [Pubmed|24261876]The protein
Catalyzed reaction/ biological activity
N-acetyl-LL-2,6-diaminopimelate + H2O --> acetate + LL-2,6-diaminopimelate [Pubmed|24261876]Protein family
peptidase M20A family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|SndA], [protein|search|SndB], [protein|search|SndC][SW|Localization]
forms uniformly distributed foci in the cytoplasm [Pubmed|24261876][SW|Interactions]
forms dimers [Pubmed|24261876][protein|search|DapI]-[protein|search|MreB] [Pubmed|24261876]References
