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cypX [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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cypX [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase
locus
BSU35060
pI
5.00
mw
45.00 kDa
function
biosynthesis of the extracellular iron chelate pulcherrimin
product
cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.3|Acquisition of iron / Other]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.1|Acquisition of iron / Other]
  • [SW|Categories] containing this gene/protein

  • [SW|acquisition of iron], [SW|electron transport/ other], [SW|iron metabolism]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon]
  • [SW|PchR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,602,588 -> 3,603,805

    The protein

    Catalyzed reaction/ biological activity

  • implicated in the three-step oxidative transformation of the diketopiperazine cyclo-l-leucyl-l-leucyl into pulcherriminic acid [Pubmed|20690619]
  • Protein family

  • [SW|cytochrome P450] family (according to Swiss-Prot)
  • Structure

  • [PDB|3NC3] [Pubmed|20690619]
  • Expression and Regulation

    Operon

  • ''[protein|search|yvmC]-[protein|search|cypX]'' [http://www.liebertonline.com/doi/pdf/10.1089/ind.2006.2.66 Reference]
  • Regulatory mechanism

  • [protein|search|AbrB]: transcription repression [Pubmed|20817675]
  • References

  • 20690619,20817675,4204912,27542896