SubtiBank SubtiBank
ftsY
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ftsY

signal recognition particle
locus
BSU_15950
pI
5.08
mw
36.19 kDa
protein length
329 aa Sequence Blast
gene length
990 bp Sequence Blast
function
protein secretion
product
signal recognition particle
essential
yes
synonyms
srb
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,670,140 → 1,671,129

    Phenotypes of a mutant

  • essential [Pubmed|28189581]

    • The protein

    Protein family

  • GTP-binding SRP family (with [protein|BB6F5D7463EF96E2C6344D0BC30A227C5E3B5817|FlhF] and [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|Ffh], according to UniProt)

    • Structure

  • [PDB|2XXA] (complex [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|Ffh]-[protein|D519765BF5261E48512CE86245BD7B733F188D4A|FtsY]-[protein|097C817A5A3E31F73F6ABC4AA95852A64E43A057|Scr] RNA, from ''E. coli'') [Pubmed|21330537]

    • [SW|Localization]

  • cell membrane, peripheral, via N-terminal lipid-binding domain [Pubmed|19414018]

    • Expression and Regulation

    Operons

    genes
    [gene|D519765BF5261E48512CE86245BD7B733F188D4A|ftsY]
    description
    [Pubmed|11021934]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|11021934], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|11021934], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]

    • regulatory mechanism

  • [protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE]: activation, [Pubmed|11021934], in [regulon|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE regulon]

    • regulation

  • expressed during vegetative growth and during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|11021934]
    • view in new tab

    genes
    [gene|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|rnc]-[gene|0136394A52759CEEDD8DE074ED74033C6FFB8435|smc]-[gene|D519765BF5261E48512CE86245BD7B733F188D4A|ftsY]
    description
    [Pubmed|11021934]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|11021934], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

    • regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]

    • regulation

  • expressed during vegetative growth and during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|11021934]
    • view in new tab

    References

    Reviews

  • 25212246,27890920

    • Original publications

  • 16705751,15995216,11021934,21330537,23563142,21255212,27355662,19414018,28189581