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ahpC [Mon Jul 11 2016 18:44:22 GMT+0200 (CEST)]

alkyl hydroperoxide reductase (small subunit)

locus

BSU40090

4.00

20.00 kDa

function

resistance against peroxide stres

product

alkyl hydroperoxide reductase (small subunit)

essential

1.11.1.15

synonyms

perR

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue]

[SW|Categories] containing this gene/protein

[SW|resistance against oxidative and electrophile stress], [SW|phosphoproteins], [SW|most abundant proteins]

This gene is a member of the following [SW|regulons]

[SW|PerR regulon]

Gene

Coordinates on the chromosome (coding sequence)

4,118,950 -> 4,119,513

The protein

Catalyzed reaction/ biological activity

2 R'-SH ROOH = R'-S-S-R' H₂O ROH (according to Swiss-Prot)

Protein family

ahpC/TSA family (according to Swiss-Prot)

Paralogous protein

[SW|AhpA]

Modification

phosphorylated on ser/ thr/ tyr [Pubmed|16493705]

Structure

[PDB|1WE0] (from ''Amphibacillus xylanus'', 78% identity, 88% similarity) [Pubmed|15770647]

[SW|Interactions]

[SW|AhpC]-[SW|AhpF] [Pubmed|15581580]

Expression and Regulation

Operon

[SW|Sigma factor]

[protein|search|SigA] [Pubmed|8932314]

Regulation

induced by H2O2 ([protein|search|PerR]) [Pubmed|11532148]

Regulatory mechanism

[protein|search|PerR]: transcription repression [Pubmed|11532148]

Additional information

belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]

References

11532148,15378759,8932314,8932315,11532148,16493705,15581580,15770647