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ydiP
similar to DNA-3-methyladenine glycosidase II
function
BsuM DNA modification
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.4|DNA restriction/ modification][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.5|Prophage 3][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]Gene
Coordinates
656,528 → 657,697
Phenotypes of a mutant
essential [Pubmed|12682299], mutation is only possible in a ''[gene|4BD4CFB10700907DF1BBF3C9CFACAF573588E85F|ydiR]'', ''[gene|A8C606348C8C6FC3BB9786C06C9BFE9D3519A041|ydiS]'', or ''[gene|D36B91B3C8EAFEB80A7395C62A50A5F80B8CC5C5|ydjA]'' background (''i. e.'', in the absence of the BsuM DNA restriction system) [Pubmed|11751814]The protein
Catalyzed reaction/ biological activity
2'-deoxycytidine in DNA + S-adenosyl-L-methionine --> 5-methyl-2'-deoxycytidine in DNA + H+ + S-adenosyl-L-homocysteineProtein family
[SW|Methyltransferase superfamily] (according to UniProt)[SW|class I-like SAM-binding methyltransferase superfamily] (according to UniProt)[SW|Domains]
SAM-dependent MTase C5-type domain (aa 1-299) (according to UniProt)Structure
[PDB|1DCT] (from Haemophilus aegyptus, 26% identity) [pubmed|7606780]Expression and Regulation
Operons
genes
[gene|9EE25F97B2C6240E31BA1D5EEE9DA2D7940C9637|ydiO]-[gene|CEA337DD4C7DFC22247FDA7FA1E71356FB819C77|ydiP]
description
[Pubmed|11751814]
regulatory mechanism
[protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]regulation
induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]view in new tabReferences
16267290,11751814,22092861,7606780 
