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fadH [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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fadH [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

2,4-dienoyl-CoA reductase
locus
BSU14060
pI
6.50
mw
26.00 kDa
function
fatty acid degradation
product
2,4-dienoyl-CoA reductase
essential
no
ec
1.3.1.34
synonyms
ykuF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.3|Utilization of fatty acids]

    • [SW|Categories] containing this gene/protein

  • [SW|utilization of lipids]

    • This gene is a member of the following [SW|regulons]

  • [SW|FadR regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,478,072 -> 1,478,836

    The protein

    Catalyzed reaction/ biological activity

  • Trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH (according to Swiss-Prot)

    • Protein family

  • 2,4-dienoyl-CoA reductase subfamily (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • ''[protein|search|fadH]-[protein|search|fadG]'' [Pubmed|17189250]

    • Regulation

  • induced in the presence of long-chain fatty acids ([protein|search|FadR]) [Pubmed|17189250]

    • Regulatory mechanism

  • [protein|search|FadR]: transcription repression [Pubmed|17189250]

    • References

  • 17189250,17919287