SubtiBank SubtiBank
thiF [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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thiF [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

hydroxyethylthiazole phosphate biosynthesis
locus
BSU11700
pI
5.62
mw
36.00 kDa
function
biosynthesis of thiamine
product
unknown
essential
no
synonyms
yjbU
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.3|Biosynthesis/ acquisition of thiamine]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors]

    • This gene is a member of the following [SW|regulons]

  • [SW|Thi-box]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,245,808 -> 1,246,818

    The protein

    Paralogous protein(s)

  • [protein|search|MoeB]

    • Structure

  • [PDB|1ZFN] (from ''E. coli'', 35% identity, 51% similarity) [Pubmed|15896804]

    • Expression and Regulation

    Operon

  • ''[protein|search|tenA]-[protein|search|tenI]-[protein|search|thiO]-[protein|search|thiS]-[protein|search|thiG]-[protein|search|thiF]-[protein|search|thiD]'' [Pubmed|1898926]

    • Regulation

  • repressed by thiamine ([protein|search|Thi-box]) [Pubmed|16356850]

    • Regulatory mechanism

  • [protein|search|Thi-box]: [SW|RNA switch] [Pubmed|16356850]

    • References

    Reviews

  • 19348578,10382260

    • Original publications

  • 14567704,15896804,1898926,16356850