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qoxB [Mon Feb 01 2016 10:35:53 GMT+0100 (CET)]
cytochrome aa3 quinol oxidase (subunit I)
product
cytochrome aa3 quinol oxidase (subunit I)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.1|Terminal oxidases][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|respiration], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|stringent response]Gene
Coordinates on the chromosome (coding sequence)
3,915,319 -> 3,917,268
Phenotypes of a mutant
inactivation of ''[protein|search|qoxB]'' restores beta-lactam resistance in a ''[protein|search|sigM]'' mutant [Pubmed|22211522]inactivation of ''qoxB'' facilitates without a wall (due to reduction of oxidative stress) [Pubmed|26051891]The protein
Catalyzed reaction/ biological activity
Ubiquinol-8 O2 = Ubiquinone-8 H2O (according to Swiss-Prot)Protein family
heme-copper respiratory oxidase family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|CtaD][SW|Cofactors]
Cu(B) [Pubmed|10837475][SW|Localization]
cell membrane [Pubmed|18763711]Expression and Regulation
Operon
''[protein|search|qoxA]-[protein|search|qoxB]-[protein|search|qoxC]-[protein|search|qoxD]'' [Pubmed|1316894]Regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]References
11073895,1316894,20351111,10551842,18763711,21821766,10837475,24779955,22211522,26196462,26051891