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spoVAF
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spoVAF

essential for the uptake of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2 ) into developing spores, required for spore maturation
locus
BSU_23390
pI
6.21
mw
55.44 kDa
protein length
493 aa Sequence Blast
gene length
1482 bp Sequence Blast
function
spore maturation
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    2,438,372 → 2,439,853

    Phenotypes of a mutant

  • delayed germination with germinant receptor-dependent germinants [Pubmed|24682327]

    • The protein

    Protein family

  • [SW|GerABKA family] (according to UniProt)

    • [SW|Localization]

  • integral inner spore membrane protein [Pubmed|24682327]

    • Expression and Regulation

    Operons

    genes
    [gene|5410018998EC9792A69CF0D9C438EEF5AC8A82C5|spoVAA]-[gene|AEC70413BDC29F435776D532E7049AA9A0BD893D|spoVAB]-[gene|B280951A232E941FB0A6C8834049765BE1E16437|spoVAC]-[gene|9531F0A0DC4AE5696FFBAC9C2A773F15840E3255|spoVAD]-[gene|31D6CB7EC20C39C1815CA4552B8B9C4BE304E86B|spoVAEB]-[gene|B44529B69769D7AF1010E06C95E398EA91A3E798|spoVAEA]-[gene|CBE5093DFBBCE25071CCE12408BC9AFF7A158C03|spoVAF]-[gene|02F1C926D200DE85C93A0ACEF23AD25FBD12B0BD|lysA]
    description
    [Pubmed|7934830]

    sigma factors

  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]: sigma factor, [Pubmed|15699190,1903432], in [regulon|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG regulon]

    • regulatory mechanism

  • [protein|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|SpoVT]: activation, [Pubmed|8755877], in [regulon|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|SpoVT regulon]

    • regulation

  • expressed late during sporulation in the forespore ([protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG], [SW|SpoVT]) [Pubmed|15699190,1903432,8755877]
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    Biological materials

    Mutant

  • BKE23390 (Δ[gene|CBE5093DFBBCE25071CCE12408BC9AFF7A158C03|spoVAF]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE23390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ACGGTTTTTGAAATACTCTT, downstream forward: _UP4_TAATCGCATTGAAACTGACT
  • BKK23390 (Δ[gene|CBE5093DFBBCE25071CCE12408BC9AFF7A158C03|spoVAF]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK23390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ACGGTTTTTGAAATACTCTT, downstream forward: _UP4_TAATCGCATTGAAACTGACT

    • References

  • 3114420,11751839,15451103,3926949,17158659,6432957,7934830,22328679,15699190,1903432,8755877,21398556,24682327,26731423