SubtiBank SubtiBank
pksE [Mon Aug 31 2015 13:54:27 GMT+0200 (CEST)]
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pksE [Mon Aug 31 2015 13:54:27 GMT+0200 (CEST)]

involved in polyketide synthesis
locus
BSU17120
pI
7.38
mw
85.00 kDa
function
polyketide synthesis
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds]

    • [SW|Categories] containing this gene/protein

  • [SW|miscellaneous metabolic pathways], [SW|biosynthesis of antibacterial compounds]

    • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|CodY regulon]

    • Expression and Regulation

    Operon

  • ''[protein|search|pksC]-[protein|search|pksD]-[protein|search|pksE]-[protein|search|acpK]-[protein|search|pksF]-[protein|search|pksG]-[protein|search|pksH]-[protein|search|pksI]-[protein|search|pksJ]-[protein|search|pksL]-[protein|search|pksM]-[protein|search|pksN]-[protein|search|pksR]'' [Pubmed|22383849]

    • Regulation

  • expressed during the transition from growth to stationary phase ([protein|search|AbrB], [protein|search|CodY]) [Pubmed|24187085]
  • repressed by glucose (6-fold) [Pubmed|12850135]

    • Regulatory mechanism

  • [protein|search|AbrB]: transcription repression [Pubmed|24187085]
  • [protein|search|CodY]: transcription activation [Pubmed|24187085]

    • References

  • 12850135,17190806,22383849,24187085