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sndB [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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sndB [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

sulphur compound N-deacetylase, the yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ operon may be implicated in the utilization of a modified cysteine variant
locus
BSU39470
pI
5.32
mw
41.00 kDa
function
unknown
product
sulphur compound N-deacetylase
essential
no
synonyms
yxeP
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.3|Conversion of S-(2-succino)cysteine to cysteine]
  • [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]

    • [SW|Categories] containing this gene/protein

  • [SW|poorly characterized/ putative enzymes]

    • This gene is a member of the following [SW|regulons]

  • [SW|CymR regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    4,056,870 -> 4,058,012

    Phenotypes of a mutant

  • a ''[protein|search|sndA] [protein|search|sndB] [protein|search|sndC]'' triple mutant does not grow with N-acetyl cysteine [Pubmed|23944997]

    • The protein

    Protein family

  • peptidase M20 family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|search|SndA], [protein|search|SndC], [protein|search|DapI]

    • Structure

  • [PDB|1YSJ]

    • Expression and Regulation

    Operon

  • ''[protein|search|yxeK]-[protein|search|snaB]-[protein|search|yxeM]-[protein|search|yxeN]-[protein|search|yxeO]-[protein|search|sndB]-[protein|search|yxeQ]'' [Pubmed|10746760]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|16513748]

    • Regulation

  • repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16513748]

    • Regulatory mechanism

  • [protein|search|CymR]: transcription repression [Pubmed|16513748]

    • References

  • 10746760,23944997,16513748