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papB
function
degradation of proline-containing peptides
product
Xaa-Pro amino-peptidase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]Gene
Coordinates
1,453,691 → 1,454,782
The protein
Protein family
peptidase M24B family (with [protein|33886A1EAC13B684E92BF94201C46617AD2844B3|PapA], according to UniProt)Paralogous protein(s)
[protein|33886A1EAC13B684E92BF94201C46617AD2844B3|PapA] Structure
[PDB|3Q6D] (''B. anthracis'' Xaa-Pro dipeptidase, 35% identity, 55% similarity)Expression and Regulation
Operons
genes
[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]
description
[Pubmed|22383849]
view in new tabgenes
[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]-[gene|6FDE01EEFCDB2F949A902DFD76A341410B867E88|ykvZ]-[gene|BC0DF593AE969F1DBC5E9E2BACF1C00BE4FEE449|glcT]
description
[Pubmed|22383849]
view in new tabBiological materials
Mutant
MGNA-B330 (ykvY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1329 NBRP B. subtilis, Japan]BKE13860 (Δ[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE13860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTCTTGTTCCTCCCTGC, downstream forward: _UP4_TAATAGAAATAAAAAAGGACBKK13860 (Δ[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK13860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTCTTGTTCCTCCCTGC, downstream forward: _UP4_TAATAGAAATAAAAAAGGACReferences