SubtiBank SubtiBank
yqiD [Wed Jan 06 2016 10:57:22 GMT+0100 (CET)]
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yqiD [Wed Jan 06 2016 10:57:22 GMT+0100 (CET)]

geranyltransferase
locus
BSU24280
pI
5.00
mw
29.00 kDa
function
biosynthesis of peptidoglycan and teichoic acid
product
geranyltransferase
essential
no
ec
2.5.1.10
synonyms
ispA

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.3|Biosynthesis of isoprenoids]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of lipids]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,525,789 -> 2,526,679

    Phenotypes of a mutant

  • The mutation of ''yqiD'' predisposes cells to grow without a wall [Pubmed|19212404]
  • The protein

    Catalyzed reaction/ biological activity

  • dimethylallyl pyrophosphate 2 isopentanyl pyrophosphate -> farnasyl pyrophosphate
  • Paralogous protein(s)

  • [protein|search|HepT]
  • Modification

  • None
  • [SW|Cofactors]

  • Magnesium
  • Structure

  • [PDB|1RQI]: IspA from ''E. coli''. Co-crystal with substrate isopentyl pyrophosphate and substrate analogue dimethyallyl S-thiolodiphosphate [Pubmed|14672944]
  • References

  • 14672944,17114254,19212404,17458547