NADPH:ferredoxin oxidoreductase
product
NADPH:ferredoxin oxidoreductase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.4|Electron transport/ other/ based on similarity][SW|Categories] containing this gene/protein
[SW|electron transport/ other]This gene is a member of the following [SW|regulons]
[SW|Fur regulon]Gene
Coordinates on the chromosome (coding sequence)
352,858 -> 353,868
The protein
Catalyzed reaction/ biological activity
2 reduced ferredoxin NADP H = 2 oxidized ferredoxin NADPH (according to Swiss-Prot)Protein family
ferredoxin--NADP reductase type 2 family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|YumC][SW|Cofactors]
FAD [Pubmed|25826316]Additional information
The gene is annotated in KEGG as an ortholog of thioredoxin reductase (NADPH) EC 1.8.1.9. In MetaCyc the protein is marked as “similar to thioredoxinreductase”. No EC annotation is available in Swiss-Prot. No literature/experimental evidence supporting the annotation is available. [Pubmed|19935659]Expression and Regulation
Operon
''ycgT'' (according to [http://dbtbs.hgc.jp/COG/prom/ycgT.html DBTBS])Regulation
induced under conditions of iron starvation ([protein|search|Fur]) [Pubmed|16672620]Regulatory mechanism
[protein|search|Fur]: transcription repression [Pubmed|16672620]Additional information
the mRNA is very stable (half-life > 15 min) [Pubmed|12884008]Biological materials
Mutant
GP1851 (aphA3), available in [SW|Jörg Stülke]'s labGP1852 (cat), available in [SW|Jörg Stülke]'s labReferences
12884008,16672620,25826316 
