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ccpB
transcriptional regulator ([SW|LacI family])
product
transcriptional regulator ([SW|LacI family])
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]Gene
Coordinates
4,196,786 → 4,197,721
The protein
Protein family
[SW|LacI family][SW|Domains]
[SW|HTH lacI-type domain] (aa 1-56) (according to UniProt)Structure
[PDB|2HSG] (B. megaterium [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA], 30% identity) [pubmed|17500051]Expression and Regulation
Operons
genes
[gene|38CC84343C47CBF37F007E9056A9248869C396E1|exoA]-[gene|C14B113B1A8BEA0547459AA7EC5755634D1A8A88|ccpB]
description
(according to [http://dbtbs.hgc.jp/COG/prom/exoA-ccpA.html DBTBS]) null
sigma factors
[protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]: sigma factor, [Pubmed|16237020], in [regulon|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG regulon]regulation
expressed late during sporulation in the forespore ([protein|search|SigG]) [Pubmed|16237020]view in new tabBiological materials
Mutant
MGNA-B867 (yyaG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1866 NBRP B. subtilis, Japan]BKE40870 (Δ[gene|C14B113B1A8BEA0547459AA7EC5755634D1A8A88|ccpB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTTTCTCCTTTTCAT, downstream forward: _UP4_TGAACTGAAATGCATTTCATBKK40870 (Δ[gene|C14B113B1A8BEA0547459AA7EC5755634D1A8A88|ccpB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTTTCTCCTTTTCAT, downstream forward: _UP4_TGAACTGAAATGCATTTCATReferences
9457849,16237020,9457849,17500051