GTP-binding protein/ GTPase
product
GTP-binding protein/ GTPase
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.3|GTP-binding proteins][category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function][SW|Categories] containing this gene/protein
[SW|GTP-binding proteins], [SW|proteins of unknown function]This gene is a member of the following [SW|regulons]
[SW|ComK regulon]Gene
Coordinates on the chromosome (coding sequence)
4,199,843 -> 4,200,943
The protein
Catalyzed reaction/ biological activity
Binds and hydrolyzes GTP and readily exchanges GDP for GTPProtein family
EngD subfamily (according to Swiss-Prot) Era/Obg familyParalogous protein(s)
[protein|search|Era], [protein|search|Obg], [protein|search|YphC], [protein|search|YsxC], [protein|search|RbgA], [protein|search|YqeH], [protein|search|ThdF], [protein|search|YyaF], [protein|search|YnbA]Expression and Regulation
Operon
''[protein|search|yyaF]-[protein|search|rpsF]-[protein|search|ssbA]-[protein|search|rpsR]'' [Pubmed|14762004]Regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165][protein|search|ComK]: transcription activation [Pubmed|11948146]Biological materials
Expression vector
for expression/ purification from ''B. subtilis'' with N-terminal Strep-tag, for [SW|SPINE], in [SW|pGP380]: pGP836, available in [SW|Stülke] labfor expression/ purification from ''E. coli'' with N-terminal His-tag, in [SW|pWH844]: pGP844, available in [SW|Stülke] labLabs working on this gene/protein
[SW|Naotake Ogasawara], Nara, JapanReferences
Reviews
Original publications
12427945,14762004,11948165,11948146 
