trehalose-specific phosphotransferase system, EIIBC component of the PTS
function
trehalose uptake and phosphorylation
product
trehalose-specific phosphotransferase system, EIIBC component
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.2|Phosphotransferase system] → [category|SW 1.2.2.2|Sugar specific PTS proteins][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.20|Utilization of trehalose][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.3|Phosphorylation on a Cys residue][SW|Categories] containing this gene/protein
[SW|phosphotransferase systems], [SW|utilization of specific carbon sources], [SW|membrane proteins], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|PhoP regulon], [SW|TreR regulon]Gene
Coordinates on the chromosome (coding sequence)
850,367 -> 851,779
The protein
Catalyzed reaction/ biological activity
Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)Protein family
[SW|PTS] permease, sucrose permease (Scr) family [Pubmed|10627040][SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|treP]-[protein|search|treA]-[protein|search|treR]'' [Pubmed|8755887][SW|Sigma factor]
[protein|search|SigA] [Pubmed|8755887]Regulation
induced by trehalose ([protein|search|TreR]) [Pubmed|8755887]repressed by glucose ([protein|search|CcpA]) [Pubmed|18977770]expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|21636651]Regulatory mechanism
[protein|search|TreR]: transcription repression [Pubmed|8755887][protein|search|CcpA]: transcription repression [Pubmed|18977770][protein|search|PhoP]: transcription activation [Pubmed|21636651]References
8755887,9829827,18977770,8917076,21636651,10627040,22900538 
