glutamine ABC transporter (binding protein)
function
glutamine uptake
product
glutamine ABC transporter (binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.2|Uptake of amino acids][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.1|Biosynthesis/ acquisition of glutamate/ glutamine/ ammonium assimilation][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.1|Utilization of glutamine/ glutamate][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|biosynthesis/ acquisition of amino acids], [SW|glutamate metabolism], [SW|utilization of amino acids], [SW|membrane proteins], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|TnrA regulon]Gene
Coordinates on the chromosome (coding sequence)
2,803,108 -> 2,803,929
The protein
Structure
[PDB|2V25] (from ''Campylobacter jejuni'', 37% identity) [Pubmed|17631313][SW|Localization]
attached to the membrane via [protein|search|GlnM]-[protein|search|GlnP] [Pubmed|10092453][SW|Interactions]
[protein|search|GlnQ]-([protein|search|GlnM]-[protein|search|GlnP])-[protein|search|GlnH] [Pubmed|10092453]Expression and Regulation
Operon
''[protein|search|glnQ]-[protein|search|glnH]-[protein|search|glnM]-[protein|search|glnP]'' [Pubmed|12823818][SW|Sigma factor]
[protein|search|SigE] [Pubmed|15699190]Regulation
expressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|12823818]expressed during sporulation ([protein|search|SigE]) [Pubmed|15699190]Regulatory mechanism
[protein|search|TnrA]: transcription activation [Pubmed|12823818]Biological materials
Mutant
GP734 (spc), available in the [SW|Stülke] labReferences
10092453,12823818,25755103,15699190,17631313 
