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pstS [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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pstS [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

phosphate ABC transporter (binding protein)
locus
BSU24990
pI
4.85
mw
31.00 kDa
function
high-affinity phosphate uptake
product
phosphate ABC transporter (binding protein)
essential
no
synonyms
yqgG, yzmB

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.6|Uptake of ions]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism]
  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|phosphate metabolism], [SW|membrane proteins], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|PhoP regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,580,715 -> 2,581,617

    The protein

    Protein family

  • pstS family (according to Swiss-Prot)
  • Modification

  • phosphorylated on ser/ thr/ tyr [Pubmed|16493705]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • extracellular (signal peptide) [Pubmed|18957862]
  • [SW|Interactions]

  • ([SW|PstBA]-[SW|PstBB])-([protein|search|PstA]-[protein|search|PstC])-[protein|search|PstS] [Pubmed|10092453]
  • Expression and Regulation

    Operon

  • ''[protein|search|pstS]-[protein|search|pstC]-[protein|search|pstA]-[SW|pstBA]-[SW|pstBB]'' [Pubmed|9098050]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9098050]
  • Regulation

  • expressed under conditions of phosphate limitation (5000-fold induced) ([protein|search|PhoP]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed]
  • Regulatory mechanism

  • [protein|search|PhoP]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed]
  • Additional information

  • mRNA processing between '[protein|search|pstS]' and '[protein|search|pstC]' to maintain higher concentrations of [protein|search|PstS] relative to other components of the [[ABC transporter]] [PubMed|15289558]
  • Labs working on this gene/protein

  • [SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]
  • References

  • 9098050,12897025,10913081,10092453,15289558,9098050,9593301,18957862,16493705,25666134