phosphate ABC transporter (binding protein)
function
high-affinity phosphate uptake
product
phosphate ABC transporter (binding protein)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.6|Uptake of ions][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue][SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|phosphate metabolism], [SW|membrane proteins], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|PhoP regulon]Gene
Coordinates on the chromosome (coding sequence)
2,580,715 -> 2,581,617
The protein
Protein family
pstS family (according to Swiss-Prot)Modification
phosphorylated on ser/ thr/ tyr [Pubmed|16493705][SW|Localization]
cell membrane (according to Swiss-Prot)extracellular (signal peptide) [Pubmed|18957862][SW|Interactions]
([SW|PstBA]-[SW|PstBB])-([protein|search|PstA]-[protein|search|PstC])-[protein|search|PstS] [Pubmed|10092453]Expression and Regulation
Operon
''[protein|search|pstS]-[protein|search|pstC]-[protein|search|pstA]-[SW|pstBA]-[SW|pstBB]'' [Pubmed|9098050][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9098050]Regulation
expressed under conditions of phosphate limitation (5000-fold induced) ([protein|search|PhoP]) [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed]Regulatory mechanism
[protein|search|PhoP]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/9098050,9593301 PubMed]Additional information
mRNA processing between '[protein|search|pstS]' and '[protein|search|pstC]' to maintain higher concentrations of [protein|search|PstS] relative to other components of the [[ABC transporter]] [PubMed|15289558]Labs working on this gene/protein
[SW|Marion Hulett], University of Illinois at Chicago, USA [http://www.uic.edu/depts/bios/faculty/hulett/hulettm.shtml Homepage]References
9098050,12897025,10913081,10092453,15289558,9098050,9593301,18957862,16493705,25666134