soluble chemotaxis receptor, heme-containing O(2) sensor protein
function
movement towards oxygen
product
haem-based aerotactic transducer
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.3|Soluble chemoreceptors][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.6|Other proteins required for efficient pellicle biofilm formation][SW|Categories] containing this gene/protein
[SW|motility and chemotaxis]This gene is a member of the following [SW|regulons]
[SW|SigD regulon]Gene
Coordinates on the chromosome (coding sequence)
1,112,620 -> 1,113,918
Phenotypes of a mutant
not essential for pellicle biofilm formation, but mutant is outcompeted by the wild-type strain when competed during pellicle formation [Pubmed|26122431]NCIB3610 ''hemAT'' mutant has higher fitness than ''[protein|search|hag]'' mutant during pellicle formation [Pubmed|26122431]NCIB3610 ''hemAT''-''[protein|search|hag]'' double mutant has similar fitness to single ''[protein|search|hag]'' mutant during pellicle formation [Pubmed|26122431]The protein
Catalyzed reaction/ biological activity
required for full expression of the ''[protein|search|phoD]-[SW|tatAD]-[SW|tatCD]'' operon [Pubmed|23180473][SW|Cofactors]
hemeStructure
[PDB|1OR4] (in cyano-liganded form), [PDB|1OR6] [Pubmed|12962628][SW|Localization]
forms clusters at the cell poles [Pubmed|21515776]homogeneous cytoplasmic distribution in chain-forming cells during the logarithmic phase [Pubmed|23180473]polar foci in individual cells at later growth stages [Pubmed|23180473][SW|Interactions]
[SW|HemAT]-[SW|TatAC] [Pubmed|23180473]Expression and Regulation
Operon
''hemAT'' [Pubmed|15033535][SW|Sigma factor]
[protein|search|SigD] [Pubmed|15033535]Additional information
in minimal medium, HemAT is present with 19,000 +/- 3,900 molecules per cell [PubMed|21515776]Biological materials
Mutant
TB239 (''hemAT''::''neo'' in 168) [Pubmed|26122431]TB241 (''hemAT''::''neo'' in NCIB3610) [Pubmed|26122431]Labs working on this gene/protein
[SW|Akos T Kovacs]References
Reviews
Original publications
26122431,10676961,16819829,11481493,15033535,21515776,23180473,22564695 
