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coaA [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

type I pantothenate kinase, major enzyme

locus

BSU23760

5.89

36.00 kDa

function

biosynthesis of coenzyme A

product

pantothenate kinase

essential

2.7.1.33

synonyms

yqjS

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.4|Biosynthesis of coenzyme A]

[SW|Categories] containing this gene/protein

[SW|biosynthesis of cofactors]

Gene

Coordinates on the chromosome (coding sequence)

2,468,549 -> 2,469,508

The protein

Catalyzed reaction/ biological activity

ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate (according to Swiss-Prot)

Protein family

prokaryotic pantothenate kinase family (according to Swiss-Prot)

Structure

[PDB|1SQ5] (from ''Escherichia coli'', 49% identity, 67% similarity) [Pubmed|15136582]

Expression and Regulation

Operon

References

1328157,24784177