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dnaI [Mon Aug 31 2015 13:56:10 GMT+0200 (CEST)]
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dnaI [Mon Aug 31 2015 13:56:10 GMT+0200 (CEST)]

primosome component (helicase loader), part of the replisome
locus
BSU28980
pI
5.00
mw
35.00 kDa
function
DNA replication
product
primosome component (helicase loader)
essential
yes
synonyms
ytxA, dnaY

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [SW|Categories] containing this gene/protein

  • [SW|DNA replication], [SW|essential genes]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,963,185 -> 2,964,120

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Structure

  • [PDB|2K7R] (N-terminal domain)
  • [PDB|4M4W] (the [protein|search|DnaC]-[protein|search|DnaI]-[protein|search|DnaG] complex) [Pubmed|24048025]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot), Cytoplasm (Homogeneous) [Pubmed|16479537] forms foci, close to oriC [Pubmed|10844689]
  • [SW|Interactions]

  • [protein|search|DnaB]-[protein|search|DnaI] [Pubmed|11842108], [protein|search|DnaC]-[protein|search|DnaI] [Pubmed|10844689]
  • part of the [SW|replisome]: [protein|search|PolC]-[protein|search|HolA]-[protein|search|HolB]-[protein|search|DnaX]-[protein|search|DnaN]-[protein|search|DnaG]-[protein|search|DnaC]-[protein|search|DnaI]-[protein|search|DnaD]-[protein|search|SsbA]-[protein|search|DnaE]-[protein|search|PriA]-[protein|search|DnaB] [Pubmed|20122408]
  • part of the [SW|primosome]: [protein|search|DnaA]-[protein|search|DnaG]-[protein|search|DnaC]-[protein|search|DnaI]-[protein|search|DnaD]-[protein|search|DnaB] [Pubmed|22797751]
  • References

    Reviews

  • 22797751
  • Original publications

  • 19255093,10844689,12718886,11842108,20122408,16479537,19744498,19255093,19968790,11679082,24048025