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dnaI [2017-12-07 13:27:34]
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dnaI [2017-12-07 13:27:34]

primosome component (helicase loader), part of the replisome
locus
BSU28980
pI
5.74
mw
35.96 kDa
protein length
311 aa Sequence Blast
gene length
933 bp Sequence Blast
function
DNA replication
product
primosome component (helicase loader)
essential
yes
synonyms
ytxA, dnaY
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • Gene

    Coordinates
    2,963,185 → 2,964,120

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Structure

  • [PDB|2K7R] (N-terminal domain)
  • [PDB|4M4W] (the [protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|DnaC]-[protein|AC1B507C6B1640E9BEA1F9F01628120F3680C976|DnaI]-[protein|F7B53E8AC92DAD15544C6208C2A5B41BABA73D6D|DnaG] complex) [Pubmed|24048025]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot), Cytoplasm (Homogeneous) [Pubmed|16479537] forms foci, close to oriC [Pubmed|10844689]

    • Expression and Regulation

    Operons

    genes
    [gene|2AEF6D56D884CA6A0BD50FABD27F405DC2B506C7|dnaB]-[gene|AC1B507C6B1640E9BEA1F9F01628120F3680C976|dnaI]-[gene|72A4458679EA1451FA3B63D44C3BE93ACA8B397F|ytxB]-[gene|3EE0D03469D893515CAA4961BF923BE3A6769535|ytxC]-[gene|3E1131CFA3EDEB3865638F09BE2F6B6ED2570BE2|thrS]
    description
    [Pubmed|22383849]
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    References

    Reviews

  • 22797751,28075389

    • Original publications

  • 19255093,10844689,12718886,11842108,20122408,16479537,19744498,19255093,19968790,11679082,24048025