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mpr [Wed Jun 15 2016 16:35:15 GMT+0200 (CEST)]
extracellular metalloprotease
function
protein degradation
product
extracellular metalloprotease
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.5|Utilization of proteins][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.2|Extracellular feeding proteases][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][SW|Categories] containing this gene/protein
[SW|utilization of nitrogen sources other than amino acids], [SW|proteolysis]This gene is a member of the following [SW|regulons]
[SW|CodY regulon]Gene
Coordinates on the chromosome (coding sequence)
245,190 -> 246,131
The protein
Protein family
peptidase S1B family (according to Swiss-Prot)[SW|Localization]
extracellular (signal peptide) [Pubmed|18957862]Expression and Regulation
Operon
''[protein|search|mpr]-[protein|search|ybfJ]'' [Pubmed|12107147]Regulation
repressed by casamino acids [Pubmed|12107147]repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|25666135]Regulatory mechanism
[protein|search|CodY]: transcription repression [Pubmed|25666135]Biological materials
Mutant
BKE02240 (''ΔaprE::erm trpC2''), available at BGSCKO7 (''ΔnprE ΔaprE Δepr Δmpr ΔnprB Δvpr Δbpr''), available as BGSC 1A1133References
Reviews
Original publications
15375126,24115457,18957862,12107147,25666135 
