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yhcS
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yhcS

sortase
locus
BSU_09200
pI
7.17
mw
21.83 kDa
protein length
198 aa Sequence Blast
gene length
597 bp Sequence Blast
function
anchoring of proteins to the cell wall
product
sortase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    994,998 995,594

    The protein

    Catalyzed reaction/ biological activity

  • C-terminal anchoring of proteins to the cell wall

    • Protein family

  • bacterial sortase family (with [protein|B17670494CC6F7C1138F4B4ECC0FEE8FC15609A2|YwpE], according to UniProt)

    • Structure

  • [PDB|2LN7] (B. anthracis SrtD, corresponds to aa 69 - 195 of YhcS, 44% identity) [pubmed|22974341]

    • [SW|Localization]

  • membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|DAFBC470DA0FA437B117716DE899A8D3EC454672|yhcR]-[gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]
    description
    [pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-A661 (yhcS::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/661 NBRP B. subtilis, Japan]
  • BKE09200 ([gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGAATAGTGGAATAACTT, downstream forward: _UP4_TAAAAAGCCGAGGCAGTGCC
  • BKK09200 ([gene|A24243129860F1B043EBE1358FAEA57BED111BBC|yhcS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09200 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GATGAATAGTGGAATAACTT, downstream forward: _UP4_TAAAAAGCCGAGGCAGTGCC

    • References

    Reviews

  • 22026821,25845800

    • Original publications

  • 21800427,21906378,22020651,22974341