You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ypgQ

Mn²⁺-dependent pyrophosphohydrolase, hydrolyzes (deoxy)ribonucleoside triphosphate [(d)NTP] to (deoxy)ribonucleoside monophosphate and pyrophosphate

locus

BSU_21890

5.51

22.98 kDa

protein length

205 aa Sequence Blast

gene length

618 bp Sequence Blast

function

degradation of excessive or abnormal nucleotides

product

Mn²⁺-dependent pyrophosphohydrolase

essential

synonyms

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

Hide small RNAs Zoom:

categories

[category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.4|Nucleotide metabolism/ other]

Gene

Coordinates

2,303,920 2,304,537

The protein

[SW|Domains]

[SW|HD domain] (aa 22-138) [Pubmed|27062940]

[SW|Cofactors]

Mn²⁺ [Pubmed|27062940]

Structure

[PDB|5IHY] [Pubmed|27062940]

[PDB|5DQV] [Pubmed|27062940]

[PDB|5DQW] (complexed with ADP) [Pubmed|27062940]

Expression and Regulation

Operons

genes

description

[Pubmed|22383849]

view in new tab

Biological materials

Mutant

MGNA-A888 (ypgQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/888 NBRP B. subtilis, Japan]

BKE21890 ([gene|A0CC440185318F7F8665AF7A8279C79A09E35518|ypgQ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCCTTCACAAAAACACCCT, downstream forward: _UP4_TAATAGAAGGCTTGGAGCGA

BKK21890 ([gene|A0CC440185318F7F8665AF7A8279C79A09E35518|ypgQ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21890 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTCCTTCACAAAAACACCCT, downstream forward: _UP4_TAATAGAAGGCTTGGAGCGA

References

25005104,27062940