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dppA [Mon Aug 31 2015 13:53:50 GMT+0200 (CEST)]
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dppA [Mon Aug 31 2015 13:53:50 GMT+0200 (CEST)]

D-alanyl-aminopeptidase
locus
BSU12920
pI
5.19
mw
30.00 kDa
function
degradation of cell wall peptides
product
D-alanyl-aminopeptidase
essential
no
synonyms
dciAA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue]
    • syns
    dciAA

    [SW|Categories] containing this gene/protein

  • [SW|utilization of nitrogen sources other than amino acids], [SW|phosphoproteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|CodY regulon]

    • The protein

    Protein family

  • peptidase M55 family (according to Swiss-Prot)

    • Modification

  • phosphorylated on ser/ thr/ tyr [Pubmed|16493705]

    • Structure

  • [PDB|1HI9]

    • Expression and Regulation

    Operon

  • ''[protein|search|dppA]-[protein|search|dppB]-[protein|search|dppC]-[protein|search|dppD]-[protein|search|dppE]'' [Pubmed|1766371]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|1766371]

    • Regulation

  • repressed by glucose (2.9-fold) [Pubmed|12850135]
  • repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|7783641]

    • Regulatory mechanism

  • [protein|search|CodY]: transcription repression [Pubmed|7783641]

    • References

  • 18083814,12618455,1766371,19602397,7783641,1766371,12850135,16493705