SubtiBank SubtiBank
yfnG
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yfnG

similar to CDP-glucose 4,6-dehydratase
locus
BSU_07280
pI
5.34
mw
33.96 kDa
protein length
301 aa Sequence Blast
gene length
906 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    799,303 800,208

    The protein

    Protein family

  • [SW|NAD(P)-dependent epimerase/dehydratase family] (according to UniProt)

    • Paralogous protein(s)

  • [protein|90D505CAA4FAAEB6A6AF5C278E70DF714FACB4DA|SpsJ]
  • [protein|A51B5F9F86D2F7B690712B9EC181B1C07B312E02|YtcB]:

    • Structure

  • [PDB|4EGB] (from ''Bacillus Anthracis Str.Ames'', 31% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|B25AE6979AF12628780C4489FFED966C6B31968A|yfnH]-[gene|9836E90BD443F5269A43E5C69FCF2CCB22EDF65B|yfnG]-[gene|4148A3F8E256D9B1D667C28428D867B5B6B5F3CE|yfnF]-[gene|E3481379D3FEC02C35CB4BE17A5246A208C5C86D|yfnE]-[gene|1D0286ECDA32FB21737170B54A57D3FE482C6422|yfnD]
    description
    [Pubmed|22383849]

    sigma factors

  • [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|15383836], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]
  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, internal promoter in [protein|E3481379D3FEC02C35CB4BE17A5246A208C5C86D|YfnE] open reading frame [Pubmed|15383836], see [http://dbtbs.hgc.jp/COG/prom/yfnHGFED.html DBTBS] for details, in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulatory mechanism

  • [protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE]: activation, [Pubmed|26577401], in [regulon|19228BAD44E6DA3DE908DC390FDF628C18D94E65|GerE regulon]

    • regulation

  • expressed during sporulation ([protein|search|SigK]) [Pubmed|15383836]
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    Biological materials

    Mutant

  • MGNA-C325 (yfnG::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2323 NBRP B. subtilis, Japan]
  • BKE07280 ([gene|9836E90BD443F5269A43E5C69FCF2CCB22EDF65B|yfnG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07280 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTTTTCCAGAAACTCAAAT, downstream forward: _UP4_TAATGTGAAACGAGGTGAAC
  • BKK07280 ([gene|9836E90BD443F5269A43E5C69FCF2CCB22EDF65B|yfnG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07280 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTTTTCCAGAAACTCAAAT, downstream forward: _UP4_TAATGTGAAACGAGGTGAAC

    • References

  • 15383836,26577401